对甲氧基甲苯氨氧化反应研究

对甲氧基甲苯氨氧化反应研究 The Research on the Ammoxidation of p-methoxytoluene 谢光勇 XIE Guang-yong 1 2 first-author 郑穹 ZHENG Qiong 1 2 黄驰 HUANG Chi 1 2 韩其勇 HAN Qi-yong 1 2 陈远荫 CHEN Yuan-yin 1 2 武汉大学化学与分子科学学院 武汉大学化学与分子科学学院 College of Chemistry and Molecular Science, Wuhan University College of Chemistry and Molecular Science, Wuhan University 武汉大学化学与分子科学学院,湖北,武汉,430072 武汉大学化学与分子科学学院,湖北,武汉,430072 研究了用 VPO/ Si O2 催化剂由对甲氧基甲苯 （PMOT）制备大茴香腈 （PMOBN）的氨氧化反应 .在内径 2 0 mm的石英管固定床反应器上 ,分别采用正交设计法实验和单因素实验考察了反应温度、空气比、氨气比、空间速度以及催化剂活性组分中的不同磷钒比 （P/ V）对 PMOT转化率、PMOBN摩尔产率和选择性的影响 .确定最适宜的反应条件是 :P/ V为 1,温度 6 0 3K,反应物摩尔比 n（PMOT）∶ n（NH3 ）∶ n（Air） =1∶ 12∶ 30 ,空间速度 5 6 4h- 1 .在此条件下 ,PMOT转化率 98%,PMOBN摩尔产率 6 3%,选择性 6 4.3%.经气相色谱分析 ,产品纯度高于 99%. Anisonitrile has been prepared by ammoxidation of p-methoxytoluene over VPO/SiO 2 catalyst. The orthogonal tests of reaction conditions and evaluation tests of catalysts were carried out in a 20 mm inside diameter fixed-bed quartz reactor. The influences of reaction temperature, the ratio of ammonia, the ratio of air, the space velocity and different rate of phosphorus and vanadium （P/V） in the catalyst upon the conversion, molar yield and selectivity of the reaction were studied. The optimum reaction conditions are: the ratio of P and V is 1, the temperature is 603 K, n（PMOT）∶n（NH 3）∶n（Air）=1∶12∶30 and the space velocity is 564 h -1 . Under these conditions, the conversion of PMOT is 98%, the molar yield of PMOBN is 63% and selectivity is 64.3%. The purity of product is over 99% by GC. 氨氧化 对甲氧基甲苯 大茴香腈 VPO/SiO2催化剂 正交设计 ammoxidation p-methoxytoluene anisonitrile VPO/SiO 2 catalyst orthogonal test O621.25 2001-06-01 2021-04-01 6