This paper describes an improved method for peptide synthesis in column. As a carrier, we used an inorganic matrix prepared by the polymerization of a monomer trichloro-[3-（4-chloromethyl phenyl） propyl] silane on porous silica beads. The first amino acid was connected with the carboxyl group to benzylic group of silicone layer. The carrier was packed in the column of a simple peptide synthesis apparatus. A more simplified program （only 8 unit operations, were needed for the incorporation of one amino acid residue） was used to synthesize Leu-enkephalin, H. Tyr. Gly. Gly. Phe. Leu.OH. and Antamanide analogue linear Decapeptide, H.Pro. Pro. Phe. Phe. Leu. Pro. Pro. Phe. Phe. Leu. OH.A symmetrical anhydride technique was empolyed for the coupling. The synthesized peptide was liberated directly in column by the use of 4 N HBr/AcOH solution. The results showed that the improved method for peptide synthesis in column is a more convenient peptide synthesis method.