肝脑清（DE-1）输液对治疗肝性脑病和纠正氨基酸代谢失衡的作用

肝脑清（DE-1）输液对治疗肝性脑病和纠正氨基酸代谢失衡的作用 GANLAOQIN（HE-1） INFUSION IN TREATING HEPATIC ENCEPHALOPATHYAND EFFECT OF CORECTION OF PLASMA AMINO ACID IMBALANCE 何其敏 He Qimin and Kong Xiaorong first-author 孔晓荣 应用肝脑清（HE-1）输液于23例肝性脑病患者。治疗结果表明,73.9%的患者支/芳比得到改善。P<0.05,差异显著,患者由昏迷转为神志清醒。患者血浆氨基酸浓度的改变预示着肝脏坏死程度,输液前酪氨酸浓度在3.2mg/100ml以下者。神志转清并且康复出院,治愈率达62.5%。本文还指出,重症肝炎肝硬化的患者表现为两类不同的氨基酸图谱,进一步研究输液量,疗程时间和综合治疗方案是十分重要的。 GANLAOQIN（HE-1）infusion was infused in 23 hepatic encephalopatic patients. In 73.9% of the patients, rapidly neurological improvemnt was observed. The rate Val+Leu+Ileu/Phe+Tyr showed a better correction, P<0.05. The degree of tyrosine elevation can be used to predietthe extant of hepatic necrosis. 62.5% of the patients with a plasma tyrosine concentration of lower than 3.2 mg/100ml appeared an excellent neurological improvement and survived well. The marked disparity in plasma amino acid patterns between the patients with serious type and these with cirrhosis type had therapeutic implications as well. It was very important for infusional therapy of the time and the dose, and more elabrate treatments, if the amino acid patterns in plasma for the patients returned to near normal and the patients were survived ultimately. 1985-03-01 2021-04-01 3