N-醚基壳聚糖的合成及膜的结构与性能

N-醚基壳聚糖的合成及膜的结构与性能 Preparation of N-acylchitosan and Structure, Properties of their Films 郑 化 ZHENG Hua1 1 2 first-author 杜予民 DU Yu-min1 1 2 武汉理工大学化学工程系 武汉理工大学化学工程系 College of Resource and Environmental Science, Wuhan University College of Resource and Environmental Science, Wuhan University 武汉大学环境科学系 湖北 武汉430070武汉大学环境科学系湖北,武汉,430072 武汉大学环境科学系 湖北 武汉430070武汉大学环境科学系湖北,武汉,430072 Department of Chemical Engineering, Wuhan University of Technology Department of Chemical Engineering, Wuhan University of Technology 以甲醇和醋酸为介质,通过酸酐与壳聚糖反应合成出N-酰基壳聚糖,并以溶液法制备出N-酰基壳聚糖膜.实验结果表明,降低醋酸浓度,增大甲醇用量以及酸酐/氨基摩尔比可提高壳聚糖的N-酰基取代度;控制醋酸和甲醇浓度以及酸酐/氨基摩尔比可获得不同取代度的N-酰基壳聚糖;N-酰基壳聚糖较为合适的合成条件为:ω（MeOH）80％、ω（AcOH）1％、酸酐/氨基摩尔比0-3.N-位长脂肪链的导入,破坏了壳聚糖原有的晶体结构,随着N-酰基脂肪链数的增长,N-酰基壳聚糖的结晶度逐渐减小,力学性能逐渐降低. N-acylchitosan prepared by reaction between carboxylic anhydride and chitosan in CH3OH and acetic acid （AcOH） , as the medium of reaction, and films of N-acylchitosan prepared from their solution. Degree of substitution （DS） of N-acylchitosan can be enhanced by decreasing the concentration of acetic acid, increasing CH3OH and the carboxylic anhydride/-NH2 molar ratio. Therefore the optimum condition is evaluated as 80% n（CH3OH）, 1% n（AcOH） and 0-3 of carboxylic anhydride/-NH2 molar ratio. The X-RD results showed that N-acylchitosan exhibited new crystalline structure. Their crystalline degree decreased with an increase of N-acrylaliphatic chain number, but the mechanical properties decreased. 壳聚糖 N-酰基壳聚糖膜 结构表征 chitosan film of N-acylchitosan structure and property O636.1 国家自然科学基金资助项目（29977014） 2002-02-01 2021-04-01 2