两亲分子有序组合体中纳米金的可控性合成

两亲分子有序组合体中纳米金的可控性合成 Synthesis and Size Control of Gold Nanoparticles in Regular System of Amphiphilic Molecules 原 弘 YUAN Hong 1 2 first-author 刘小玲 LIU Xiao-ling 1 2 蔡汝秀 CAI Ru-xiu 1 2 庞代文 PANG Dai-wen 1 2 武汉大学化学与分子科学学院 武汉大学化学与分子科学学院 College of Chemistry and Molecular Sciences, Wuhan University College of Chemistry and Molecular Sciences, Wuhan University 武汉大学化学与分子科学学院,湖北,武汉,430072 武汉大学化学与分子科学学院,湖北,武汉,430072 介绍了氯金酸直接还原法制备胶体金的改进方法,通过本方法获得了分散性好、粒径在5-14nm的金纳米颗粒.结合表面活性剂的两亲性和纳米微粒本身的高比表面积引起的金粒子电荷表面分布变化,探讨了两亲分子有序组合体在纳米合成中的作用,研究表明SDS在纳米颗粒形成过程中先与Au3+形成复合体,同时在Au3+被还原为Au并聚集成纳米颗粒时SDS起到了稳定剂和分散剂的作用,阻止了纳米金的进一步团聚,使金粒子的粒径分散比较均匀,尺度可控.初步结果表明本方法制备的纳米金颗粒对蛋白质（如BSA等）有良好的吸附性能,并有可能发展简便快速的蛋白质测定方法. Two synthetic techniques for colloidal gold particles was improved by using SDS. And colloidal Au particles of mean diameters between 5 and 14 nm are synthesized, that exhibit improved monodis-persity relative to previously published methods. According to the particular molecular structure of surfactants and different electrons distribution arising from colloidal small sizes and high surface/volume ratios, it is found that there are a complex between SDS and Au3+ （and Au atoms ） during synthesizing colloidal gold nanoparticles and as a stablizer for Au particles, SDS can prevent their further growth. So the colloidal gold particles is monodispersize and more steady. But other surfactants don’t affect the process of synthesizing gold nanoparticles because of their structures and properties different from SDS. Gold nanoparticles have considerable bioaffinity and can be applied to study the adsorption of proteins or polypeptides. 纳米金粒子 SDS 分散性 nanoparticle gold SDS size distribution O614 武汉市重大科研专项项目资助（20016009107） 2002-02-01 2021-04-01 2