壳聚糖季铵盐分子结构与吸湿保湿性研究

壳聚糖季铵盐分子结构与吸湿保湿性研究 Effect of Molecular Structure on Moisture Absorption and Retention Capacity of 2-Hydroxypropyltrimethyl Ammonium Chloride Chitosan 樊木 FAN Mu 1 2 first-author 肖玲 XIAO Ling 1 2 杜予民 DU Yu-min 1 2 武汉大学资源与环境科学学院 武汉大学资源与环境科学学院 College of Resources and Environmental Sciences, Wuhan University College of Resources and Environmental Sciences, Wuhan University 武汉大学资源与环境科学学院,湖北,武汉,430072 武汉大学资源与环境科学学院,湖北,武汉,430072 采用不同反应和降解条件制备了一系列不同取代度和不同分子量的羟丙基三甲基氯化铵壳聚糖（HACC） .通过红外光谱、核磁共振谱和凝胶渗透色谱对结构进行表征 ,同时测量HACC的吸湿保湿性能 ,并与透明质酸 （HA）、乳酸钠进行比较 .结果表明 :HACC的保湿性能随分子量增加而增大 ,而吸湿性能却随分子量增加而减小 ;取代度小于 43 %时 ,HACC的吸湿保湿性能急剧减小 ;取代度大于 43 %时 ,HACC具有比HA更好的吸湿性能 ,而其保湿性能和HA基本持平 A series of 2-Hydroxypropyltrimethyl Ammonium Chloride Chitosan（HACC） with different degree of quaternarization and molecular weight were prepared. Molecular weight and structure of HACC was characterized by gel permeation chromatography, infrared spectrum and 13C NMR. The moisture absorption and moisture retention properties of HACC were found similar to those of hyaluronic acid. The moisture absorbability increased with decreasing in molecular weight and moisture retention capacity increased with increasing in molecular weight. The moisture absorption and moisture retention ability decreased when degree of quaternarization was less than 43%. 壳聚糖季铵盐 壳聚糖 分子量 吸湿 保湿 hydroxypropyltrimethyl ammonium chloride chitosan chitosan molecular weight moisture absorption moisture retention O636.1 国家自然科学基金资助项目 （ 2 99770 14 ） 2003-02-01 2021-04-01 2