有机胂化合物的研究——ⅩⅨ.应用胂叶立德合成三元环衍生物的探讨

有机胂化合物的研究——ⅩⅨ.应用胂叶立德合成三元环衍生物的探讨 STUDIES ON ORGANOARSENIC COMPOUNDS Ⅹ Ⅸ.Probing on Synthesis Cyclopropane Derivatives by Arsonium Ylides 陶文田 Tao Wentian Liu Jide 1 first-author 刘继德 1 武汉大学化学系 武汉大学化学系 Department of Chemistry,Wuhan University Department of Chemistry,Wuhan University 报道了三种用胂叶立德制备环丙烷衍生物的方法:①胂叶立德1进行热裂解,得到环丙烷衍生物2.②胂叶立德1与α,β-不饱和酮（3a-c）反应,得到立体专一性的环丙烷衍生物（4a-c）.③砷盐5在两相体系中与α,βr不饱和酮（6a-e）进行相转移反应,获得立体专一性的环丙烷衍生物（7a-e）.所有产物经元素分析、红外光谱、核磁共振谱和质谱确证了结构。 This paper presents cyclopropane derivatives were prepared in three ways.①Pyrolysis of arsoni- um ylide 1 at 110℃ in the solvents to afford cyclopropane derivatives 2,and yields were 96%. ②Reaction of arsonium ylide 1 with α,β-unsatrate ketones(3 a-c )in solvents to afford stereoselec- tivity cyclopropane derivatives(4 a-c ),and its mechanism was discussed.③The reaction of arsonium solts 5 with α,β-unsatrate ketone in the two phase system of C 6 H 6 /H 2 O/50% NaOH to afford stereose- leetivity cyclopropane derivatives(7 a-c ).Their structure have been ascertained by elemental analysis, IR, 1 H NMR and MS spectroscopy. 砷盐 环丙烷衍生物 热裂解 arsonium solts cyclopropane verivatives pyrolysis O627.521 中国科学院金属有机化学开放实验室资助项目 1992-04-01 2021-04-01 4