甜叶醇的结构改造及生物活性试验

甜叶醇的结构改造及生物活性试验 STNTHESES AND PHYSIOLOGICAL TESTING OF NEW PGRS 刘秀芳 1 first-author 黄曦 1 徐汉生 1 武汉大学化学系 武汉大学化学系 Department of Chemistry, Wuhan University,,, 4 Department of Chemistry, Wuhan University,,, 4 本文以生源学说为理论依据，通过水解甜菊苷得到赤霉素类似物的先导母体甜叶醇和异甜叶醇，再分别对它们进行有目的的结构改造，获得一系列植物生长调节剂．其中七个新化合物均经元素分析、质谱、核磁、红外分析，确定了结构．初步的生物活性试验表明，大多数化合物在促进水稻种子发芽过程中，活性优于ＧＡ３． According to the theory of biogenesis, steviol and gibberelline are metabolites from ent-kaurene as homologous compounds. So the hydrolytic products from stevioside-steviol and isosteviol may be the precursors of analogs of GA, which will show the same bioactivity as GA. After modifying their structures, we have got a series of PGRs. All the new compounds have been verified by EA,MS, 1HNMR, IR, and most of them have apparent bioactivity in physiological testing （compared with GA3 ）. 甜菊苷 赤霉素 植物生长调节剂 生物活性 stevioside gibberelline PGR bioactivity Q944 湖北省自然科学基金(2017CFA007) 1994-02-01 2021-04-01 2