QU WANYUN, YANG CHUNHAI, ZHANG SHENGHUI. Voltammetric Behaviors of Mitoxantrone at the Multi-Wall Carbon Nanotube Modified Electrode and Its Application. [J]. 2006, (4): 439-443.
QU WANYUN, YANG CHUNHAI, ZHANG SHENGHUI. Voltammetric Behaviors of Mitoxantrone at the Multi-Wall Carbon Nanotube Modified Electrode and Its Application. [J]. 2006, (4): 439-443.DOI:
The voltammetric behavior of mitoxantrone on the MWNT modified electrode was investigated.It is found that MWNT film significantly enhances the oxidation peak current of mitoxantrone.All the experimental parameters were optimized
and a sensitive electrochemical method was developed for the determination of mitoxantrone.The oxidation peak current is linear with the concentration of mitoxantrone from 2.8×10
-8
to 1.1×10
-6
mol·L
-1
.The detection limit is about 5.6×10
-9
mol·L
-1
for 4 min accumulation.The relative standard deviation(n=10) was 4.6% for 1.0×10
-7
mol·L
-1
mitoxantrone.This method can be successfully used in the determination of content of mitoxantrone in mitoxantrone injections.