杂芳基硼化合物的合成

杂芳基硼化合物的合成 Preparation of Heteroarylboron Compounds 黄世文 HUANG Shi wen 1 first-author 单自兴 SHAN Zi xing 1 黄金昆 HUANG Jin kun 1 赵德杰 ZHAO De jie 1 武汉大学化学学院 武汉大学化学学院 College of Chemistry,Wuhan University,Wuhan 430072,China) \ \ College of Chemistry,Wuhan University,Wuhan 430072,China) \ \ 利用２－溴噻吩、镁屑、硼酸三正丁酯或三氟化硼乙醚室温下一锅反应分别合成了一噻吩基、二噻吩基硼酸，三噻吩基硼烷及其衍生物．利用５－甲基－２－呋喃基锂、２－苯并呋喃基锂与硼酸三正丁酯或三氟化硼乙醚低温下反应合成了几种含呋喃基硼化合物．利用烃基格氏试剂与噻吩基硼酸正丁酯低温下反应合成噻吩基烃基硼酸衍生物 thienyl boronic acid,di（2 thienyl）borinic acid,tri（2 thienyl） borane and their deriverates were prepared by one pot reaction between 2 bromothiophene,magnesium and boron trifluoride ether or tributyl borate at room temperature .5 Methyl 2 furanyl and 2 benzofuranyl boron compounds were obtained from the corresponding lithium reagents reacting with borontrifluoride ether or tributylborate at lower temperature. 噻吩基硼化合物 5－甲基－2－呋喃基硼化合物 2－苯并呋喃基硼化合物 “一锅”格氏反应 锂试剂 thienylboron compound 5 methyl 2 furanyl boron compound 2 benzofuranyl boron compound one pot Grignard reaction lithium reagent O627.31 国家自然科学基金,武汉市晨光青年科学基金 1999-02-01 2021-04-01 2