β-环糊精与萘普生的包络反应及荧光分析

β-环糊精与萘普生的包络反应及荧光分析 Studies on the Inclusion Reaction and Fluorescence Analytical Application of β-cyclodextrin With Naproxen 潘祖亭 PAN Zu\|ting 1 first-author 孔凤华 KONG Fong\|hua 1 左超 ZUO Chao 1 武汉大学化学与环境科学学院,武汉,430072 武汉大学化学与环境科学学院,武汉,430072 The College of Chemistry and Environment Science, Wuhan University, Wuhan 430072,China) \ The College of Chemistry and Environment Science, Wuhan University, Wuhan 430072,China) \ 采用荧光光谱法系统地研究了萘普生的自身荧光现象及其与β-环糊精因包络反应而产生的荧光增敏作用,试验了在不同条件下的荧光性质,提出了测定萘普生含量的高灵敏荧光光度分析新方法. 荧光激发峰λex =229 nm ,荧光发射峰λem = 353 nm ,荧光强度（F）与萘普生的浓度在6.14×10- 8m ol·L- 1 ～1.36×10- 5m ol·L- 1范围内呈线性关系,分析方法操作简便、快速,重现性好,结果令人满意. A simple and highly sensitive spectofluorimetry has been investigated for determination of naproxen based on naproxen\’s self fluorescence and the inclusion reaction of β cyclodextrin with naproxen. The maximum excitation wavelength appears at 229 nm with fluorescence occurring at 353 nm. At the dimension of naproxen 6.14×10 -8 ～1.36×10 -5 mol·L -1 , the value F of the fluorescence intensity appears good linear relations with the contents of naproxen. The method is simple, rapid, and has good reappearance and satisfied results.\; β-环糊精 萘普生 包络反应 荧光分析 cyclodextrin naproxen inclusion reaction spectrofluorimetry Q53 国家自然科学基金!（G1999064703） 1999-06-01 2021-04-01 6