纯品枸杞多糖对小鼠抗疲劳的效果

纯品枸杞多糖对小鼠抗疲劳的效果 Effects of Pure Lycium Barbarum Polysaccharide on Antifatigue in Mice 罗琼 LUO Qiong 1 1 2 first-author 阎俊 2 1 2 张声华 YAN Jun 1 1 2 湖北医科大学卫生学教研室!武汉430071华中农业大学食科系,430070 湖北医科大学卫生学教研室!武汉430071华中农业大学食科系,430070 Department of Hygiene, Hubei Medical University Department of Hygiene, Hubei Medical University 华中农业大学食科系,430070 华中农业大学食科系,430070 Department of Food Science and Technology, Huazhong Agricultural University Department of Food Science and Technology, Huazhong Agricultural University 将纯品枸杞多糖分为５，１０，２０，５０，１００ ｍ ｇ·ｋｇ－ １ ·ｄ－ １等５ 个不同剂量的实验组，灌喂小鼠，观察其对小鼠抗疲劳的效果纯品枸杞多糖能显著地增加小鼠肌糖原、肝糖原储备量；提高运动前及游泳后 ９０ ｍ ｉｎ 及 １５０ｍ ｉｎ Ｌ Ｄ Ｈ 总活力；降低小鼠剧烈运动后血尿素氮增量，加快运动后血尿素氮的恢复速率；以１０ ｍ ｇ·ｋｇ－ １ ·ｄ－ １ 剂量组效果最佳 提示纯品枸杞多糖在提高机体对运动员负荷的适应能力，抵抗疲劳产生和加速疲劳的消除具有十分明显的作用 The purified fraction Lycium barbarum polysaccharides（LBP X）were divided into 5, 10, 20, 50 and 100 mg·kg -1 ·d -1 five different doses which were applied to mice,and study their effects on antifatigue. The results showed that all of the LBP X had a remarkable effect on building up body’s adaptability to exercise load, enhancing resistance and accelerating elimination to fatigue. LBP X five doses could enhance the reserves of muscle and liver glycogen, increase the activity of LDH before and after swimming 90min and 150min, decrease the raise content of blood urea nitrogen（BUN）after strenuous exercise, accelerate the rate of BUN recovery after exercise in tired mice. Effects of LBP X 10 mg -1 ·kg -1 ·d -1 was the best among the five doses of LBP X. 枸杞多糖 抗疲劳 量效关系 lycium barbarum polysaccharide X（LBP X） antifatigue doses response relationship R151.3 湖北省自然科学基金(2017CFA007) 1999-04-01 2021-04-01 4