N-（O,S-二甲基硫代磷酰基）α-L-氨基酸酯的合成及其杀虫活性

N-（O,S-二甲基硫代磷酰基）α-L-氨基酸酯的合成及其杀虫活性 The Synthesis of N （O,S-dimethylthiophospheryl） α-L-amino Acid Esters and Their Insecticidal Active 汤家芳 TANG Jia\|fang 1 first-author 周九元 ZHOU Jiu\|yuan 1 刘芝兰 LIU Zhi\|lan 1 肖玉秀 XIAO Yu\|xiu 1 吴正辉 WU Zheng\|hui 1 邬开朗 WU Kai\|nang 1 武汉大学生命科学学院,武汉,430072 武汉大学生命科学学院,武汉,430072 College of Life Sciences, Wuhan University College of Life Sciences, Wuhan University 从α-L-氨基酸酯在摩尔级高产率制备了光学纯N-（O,S-二甲基硫代磷酰基）α-L-氨基酸酯. 利用IR,1H-NMR,摩尔旋光鉴定了结构特征,利用生物测试法研究了杀虫活性.4 种活性氨基酸杀虫剂在0.01% ～0.001% 浓度内,它们对两令棉铃虫的触杀死亡率为100% ～80% ,胃杀死亡率为95% ～50% ,而且杀虫活性有随活性氨基酸杀虫剂分子中R-基团碳链增长而增强的趋势. N （O,S dimethylthiophospheryl）α L amino acid esters（NDTPAAE） was prepared with high yield and high optical purity from the esters α L amino acids on a molecular scale. The compounds was characterized with IR, 1H NMR, molecular rotation power and biotest. Within 0.01%～0.001% of NDTPAAE the death rate caused by contact toxicant to two age bollworm was 100% 8 0% and the death rate of stomach poison was 95% 5 0%. It was found that the longer of the carbon chain in the R group of active amino acids was the stronger of the insecticide activity indicated.\; 氨基酸 活性氨基酸 农药 杀虫剂 aminoacids active aminoacids agricultural chemicals pesticides TQ453.6 国家自然科学基金!（39522001） 1999-06-01 2021-04-01 6