对QTL复合区间作图法的一点改进

对QTL复合区间作图法的一点改进 An Improvement on Composite Interval Mapping of Quantitative Trait Loci 胡中立 HU Zhong\|li 1 first-author 武汉大学生命科学学院,湖北,武汉,430072 武汉大学生命科学学院,湖北,武汉,430072 College of Life Sciences,Wuhan University College of Life Sciences,Wuhan University 提出了“分子标记的遗传编码及其复合原则”,并构造出能够反映各级 QTL 互作效应的复合标记变量 X ,X ,… ,Xk;从理论上证明了各级复合标记变量与所有标记变量 X 之间相互独立 ,并给出了各个复合标记变量对数量性状 Y的偏回归系数的遗传学期望 .基于这些理论结果 ,进而探讨了对复合区间作图的改进方案 Principles of genetically scorring for genotypes of a individual marker and complex marker were put forward.Complex marker variables X Ⅱ,X Ⅲ,…,X k reflecting QTL interaction effect under different levels were worked out.This paperproved theoretically that complex marker variables at every level, X Ⅱ,X Ⅲ,…,X k ,are independent of all marker variable X Ⅰ .The genetic expectation of partial regression coefficients of X Ⅱ,X Ⅲ,…,X k to quantitative trait Y were also shown.Based on these results,an improved method for composite interval mapping was proposed. 复合区间作图 分子标记 复合标记变量 上位性 composite interval mapping molecular marker complex marker variable epistasis 10.14188/j.1671-8836.2000.06.027 Q348 教育部高等学校骨干教师资助计划资助 2000-06-01 2021-04-01 6