几种新型呋喃胺Schiff碱的合成

几种新型呋喃胺Schiff碱的合成 Synthesis of Some New Kinds of Furan Amine Schiff Bases 李艳 LI Yan1 1 first-author 胡杨根 HU Yanggen2 2 丁明武 DING Mingwu3 3 咸宁学院化学与生命科学学院 咸宁学院化学与生命科学学院 College of Chemistry and Life Science,Xianning College College of Chemistry and Life Science,Xianning College 郧阳医学院医学化学研究所 郧阳医学院医学化学研究所 Institute of Medicinal Chemistry,Yunyang Medical College Institute of Medicinal Chemistry,Yunyang Medical College 华中师范大学农药与化学生物学教育部重点实验室 华中师范大学农药与化学生物学教育部重点实验室 Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, Huazhong Normal University Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, Huazhong Normal University 以自制的5-甲基-4-乙氧羰基-3-腈基-2-呋喃胺与取代芳醛为主要原料,以乙醇为溶剂、醋酸为催化剂,通过回流反应以70%～85%的产率合成了8种新的5-甲基-4-乙氧羰基-3-腈基-2-呋喃胺Schiff碱化合物,产物用紫外-可见吸收光谱,红外光谱,核磁共振氢谱和质谱进行了表征. Eight new 3-cyano-4-ethoxycarbonyl-5-methyl-2-furan amine Schiff bases were synthesized from self-made 3-cyano-4-ethoxycarbonyl-5-methyl-2-furan amine and aromatic aldehydes using alcohol as dissolvent,acetic acid as the catalyst by reflux in yield of 70%-85%.Their structures were confirmed by UV-vis,IR,1H NMR and MS. 呋喃胺 Schiff碱 合成 furan amine Schiff base synthesis 10.14188/j.1671-8836.2011.01.008 TQ251.1 国家自然科学基金（20772041）资助项目 2011-01-01 2021-04-01 1 57