6种新型3-苯甲酰甲基硫代-1,2,4-三唑的合成

6种新型3-苯甲酰甲基硫代-1,2,4-三唑的合成 Synthesis of Six New Kinds of 3-Phenacylthio-1,2,4-Triazoles 刘天宝 LIU Tianbao1 1 2 first-author 彭艳芬 PENG Yanfen1 1 邹建平 ZOU Jianping3 3 池州学院材料与化学工程系 池州学院材料与化学工程系 Department of Material and Chemical Engineering,Chizhou College Department of Material and Chemical Engineering,Chizhou College 安徽大学 绿色高分子材料安徽省重点实验室 安徽大学 绿色高分子材料安徽省重点实验室 Anhui Province Key Laboratory of Environment-Friendly Polymer Materials,Anhui University Anhui Province Key Laboratory of Environment-Friendly Polymer Materials,Anhui University 苏州大学材料与化学化工学部 苏州大学材料与化学化工学部 College of Chemistry,Chemical Engineering and Materials Science,Soochow University College of Chemistry,Chemical Engineering and Materials Science,Soochow University 以1-芳酰基-3-苯氨基硫脲和2-溴代苯乙酮为主要原料,以二氯甲烷为溶剂,在弱碱三乙胺催化下合成了6种新的3-苯甲酰甲基硫代-1,2,4-三唑类化合物,产率为72%～86%,产物的结构通过红外光谱、核磁共振光谱和高分辨质谱进行了表征. Six new kinds of 3-phenacylthio-1,2,4-triazoles were synthesized from 1-aroyl-3-phenylaminothiourea and 2-bromoacetophenone using dichloromethane as dissolvent,and triethylamine as the catalyst.All the structures of compounds were confirmed by IR,1H NMR,13C NMR and HRMS spectra.The yields are about 72%-86%. 关键词,2,4-三唑 1-芳酰基-3-苯氨基硫脲 二氯甲烷 2-溴代苯乙酮 1,2,4-triazole 1-aroyl-3-phenylaminothiourea dichloromethane 2-bromoacetophenone 10.14188/j.1671-8836.2013.04.005 TQ254 国家自然科学基金（21271035）;绿色高分子材料安徽省重点实验室开放课题基金（KF2012001）资助项目 2013-04-01 2021-04-01 4 59